If you want to submit a study proposal please use the proposal form available in the documents section. All proposals will be assessed by the steering group and approved if the project is scientifically valid and does not bias the main trial. Funding and ethical approval should also be available if needed. Proposed substudies are described below. Click on the pdf for more information.
Substudies: - Submit by April 30
Studies which record extra data (for example CT on all patients) or are based on data that will not be reported in the main publication. Substudies should be approved before the start of the trial and have a seperate protocol. We strongly encourage the publication of this protocol, similarly to the analysis of cognitive outcomes in the TTM1-trial.
Studies based primarily on data already available in the study database. A detailed analysis plan is preferable, but not necessary. Post-hoc analyses may be submitted throughout the trial.
Suggestions for studies based on the TTM2-Biobank may be submitted but the steering group will not process these publications until late 2017 at the earliest.
More information will be available at a later date.