About the study
Who are we
Protocol for the TTM2 follow-up published in Resuscitaiton
15 April 2020
Protocol for outcome reporting and follow-up in the Targeted Hypothermia versus Targeted Normothermia after Out-of-Hospital Cardiac Arrest trial (TTM2)
20 March 2020
Dear TTM2 friends, We hope that all of you are well in these troubled times. The Covid-19 outbreak increasingly affects the sites of the TTM2-network. Many of...
20 January 2020
Three randomisations today in Lugano, Switzerland, Oslo University Hospital, Norway, and Örebro, Sweden, completed recruitment in TTM2. Congratulations to...
TTM2 - Trial design article (open access).
16 November 2019
The trial design article is now available with open access at the American Heart website: https://www.sciencedirect.com/science/article/pii/S0002870319301577
Formal Interim analysis
04 October 2019
Today the Data Safety Monitoring Committee (DSMC) gave the recommendation to continue randomisation as planned. Their analysis is based on the 1200...
29 May 2019
Participant no. 1000 was randomised in Bristol today. The TTM2 trial is now live at 56 locations! The trial is now well passed and the halfway mark with 900...
Investigator meeting in Lund 22 May
22 May 2019
A big welcome to everyone who will be attending the Investigator meeting in Lund today!
Largest cardiac arrest trial in an ICU setting
22 May 2019
With more than 950 participants randomized, the TTM2-trial is now the largest ever cardiac arrest trial performed in an ICU setting. With less than 950...
04 February 2019
Complex situations may arise in the trial, to clarify some potential issues we have published three FAQs. They are available in the manuals section of "...
15 January 2019
Another milestone for TTM2! 500+ participants enrolled. The first patient in the Southern Hemisphere has also been randomized at Nepean Hospital in New South...